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KMID : 0525720200250010029
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Journal of Chitin and Chitosan
2020 Volume.25 No. 1 p.29 ~ p.35
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Applications of Marine-Derived Natural Biomaterials for Bio 3D Printing
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Moon Yeon-Hee
Lim Won-Bong
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Abstract
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In this review, it is described the recent trends in materials and applications of the marine natural biological resources for the bio 3D printing technology. The bio 3D printing is additive manufacturing technology through living cell and scaffold as supporting materials such as collagen, chitosan and alginic acid as marine-derived natural biomaterials. It is known to be useful for biomaterial because of its high biocompatibility, biodegradability and low toxicity. Collagen have been widely used to bio 3D printing scaffold known to improve the wound repair since they can stimulate various cellular activities including cell proliferation, differentiation, migration, and even guidance of near cells to work as normal tissues functionally. Chitosan is widely used for preparing scaffolds for regenerative medicine because of its ability to bioresorption and biocompatibility. There are known the research in which lyophilized chitosan scaffolds were successfully tested as candidates for tissue regeneration. In addition, alginates are known to be able to fulfill the considerable requirements for suitable bioink formulation, a critical component of efficient 3D bioprinting. Taken together, through the research on 3D bioprinting using marine-derived natural materials such as collagen, chitosan, and alginic acid, it is expected to be applied to biocompatible 3D printing materials for various biomedical applications.
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KEYWORD
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3-D printing, Biomaterials, Biomedical application, Marine biodiversity, Tissue engineering
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